Glucocorticoids Hurt Recall, and Are Produced More With Age
memory loss has been linked with high levels of ‘stress’ steroid hormones known as glucocorticoids which have a deleterious effect on the part of the brain that helps us to remember. An enzyme called 11beta-HSD1 is involved in making these hormones and has been shown to be more active in the brain during ageing. …human trials will start on a drug that blocks that enzyme; effects seen in mice after 10 days of dosing.